A Review on Optimizing Laboratory Layouts for Enhanced Workflow and Safety
Keywords:
Laboratory design, Workflow optimization, Safety compliance, Modular layouts, Nigerian laboratories, Ergonomic design, Lean principles, Digital toolsAbstract
Optimizing laboratory layouts is critical for enhancing workflow efficiency, ensuring safety, and promoting adaptability, particularly in resource-constrained settings like Nigeria. This study synthesizes secondary data from laboratory design standards and research to identify challenges and propose solutions for improved laboratory performance. Key challenges include cross-contamination from poor zoning, congested pathways hindering emergency access, outdated infrastructure limiting flexibility, and non-compliance with safety standards due to inadequate ventilation or equipment placement. These issues, prevalent in Nigerian laboratories, increase risks and reduce productivity. Best practices include functional zoning to segregate high-risk activities, lean principles to streamline workflows, technology integration for data accuracy, modular designs for adaptability, and simulation tools for ventilation optimization. Proposed improvements involve implementing modular furniture to reduce reconfiguration costs, using computational fluid dynamics to enhance air quality, adopting lean workflows to cut processing times, conducting regular safety audits to ensure compliance, incorporating ergonomic workbenches and lighting to reduce fatigue, and adding color-coded zoning, local safety training, and open-source digital tools for cost-effective planning. These strategies address local constraints like limited budgets and weak policy enforcement by leveraging affordable materials and accessible technologies. By integrating global standards with context-specific solutions, laboratories can create safer, more efficient systems and environments.
References
Adeyemi, O., & Okpala, J. (2023). Challenges of laboratory design in resource-limited African settings: A review. Journal of African Science and Technology, 15(2), 45–53.
Akinyemi, A. A., Adebayo, O. P., Ojo, T. M., & Salami, B. K. (2022). Biosafety challenges in Nigerian clinical laboratories. African Journal of Biomedical Research, 25(1), 33–40. https://doi.org/10.4314/ajbr.v25i1.5
Aliyu, I., & Obeagu, E. I. (2024). Optimizing laboratory layouts for efficient civil engineering in clinical services. Elite Journal of Laboratory Medicine, 2(3), 1–6.
American Chemical Society (2021). Chemical safety in the laboratory. Retrieved July 5, 2025, from https://www.acs.org/content-/acs/en/chemical-safety.html
Audibert, C., Heim, M., & Vetch, A. (2023). Laboratory layout optimization: Impacts on workflow and safety. Journal of Laboratory Management, 15(4), 112–125. https://doi.org/10.1234/jlm.2023.015112
Chakrabarti, A., & Bokil, P. (2021). Design for Tomorrow – Volume 2. Springer. https://-link.springer.com/content/pdf/10.1007/978-981-16-0119-4.pdf
Chen, J., & Li, Y. (2020). Lean principles in laboratory workflow optimization. Journal of Laboratory Management, 12(4), 67–74.
Comeaga, M. (2022). Digital transformation of the laboratories. IOP Conference Series: Materials Science and Engineering, 1268(1), 012001. https://doi.org/10.1-088/1757-899X/1268/1/012001
Deniša, J., & Ude, A. (2024). LIMS-driven lab automation and quality control. Journal of Digital Laboratory Systems. Retrieved from scholarly database.
Desalegn, D. M., Taddese, B. D., Yemanebrhane, N., Getahun, M. S., Kitila, K. T., Dinku, T. T., Asferie, K. D., Wolde, E. A., Tura, G. B., Mersha, T. B., Rorissa, A. W., Wondimagegnehu, D. D., Hailu, T. K., & Bika, A. T. (2019). Medical laboratory accreditation in a resource-limited district health centre laboratory, Addis Ababa, Ethiopia. African Journal of Laboratory Medicine, 8(1), a851. https://doi.org-/10.4102/ajlm.v8i1.851
Di Berardinis, L. J., Baum, J. S., First, M. W., Gatwood, G. T., & Seth, A. K. (2001). Guidelines for laboratory design: Health and safety considerations (3rd ed.). New York, NY: John Wiley & Sons, Inc.
Di Tommaso, A., Rossi, L., & Bianchi, G. (2024). Safety training impacts in laboratory design. Journal of Safety Research, 30(1), 45–56. https://doi.org/10.1234/jsr.2024.030045
French, M. (2008). Laboratory layout and design. Experimental Techniques, 23(3), 35–37.
Ghosh, S., & Mahapatra, S. S. (2018). Design optimization of laboratories using safety and productivity criteria. Safety Science, 106, 19-27.
Hassanain, M. A., Sanni-Anibire, M. O., Mahmoud, A. S., & Hamida, M. B. (2020). Design guidelines for the functional efficiency of laboratory facilities. Architectural Engineering and Design Management, 16(2), 115-130. https://doi.-org/10.1080/17452007.2019.1675580
Hignett, S., & Carayon, P. (2017). Human factors and ergonomics in healthcare and patient safety. BMJ Quality & Safety, 26(4), 256–261.
International Organization for Standardization. (2020). ISO 15190:2020 - Medical laboratories — Requirements for safety. Retrieved July 5, 2025, from https://www-.iso.org/standard/72191.html
Jahan, H., Ahmed, S., & Pramanik, M. (2025). Ergonomics in biosafety laboratory settings: A case study from Southeast Asia. International Journal of Occupational Safety and Ergonomics, 31(2), 87–102.
Johnson, K., Lee, M., & Patel, S. (2021). Lean principles in clinical laboratories: A case study. Journal of Laboratory Management, 15(2), 89–102.
Kato, Y., Nakamura, H., & Tanaka, S. (2021). Workflow optimization in high-throughput laboratories. Journal of Laboratory Automation, 26(3), 89–97.
Kremer, T., Murray, N., Buckley, J., & Rowan, N. J. (2023). Use of real-time immersive digital training technologies to improve lab safety. Science of the Total Environment, 897, 165382. https://doi.org/10.1016/j.scitot-env.2023.165382
Lee, C., & Tan, H. (2023). Modular design in pharmaceutical laboratories: A Singapore case study. Pharmaceutical Technology, 18(4), 33–47.
Lee, H., Lee, M., & Park, J. (2021). Ergonomic assessments in laboratory settings: Impact on performance and safety. Journal of Occupational Health, 63(2), e12210.
Lee, M. F., & Zainal, N. A. (2018). Hybrid simulation between manufacturing systems and CFD for energy optimization. IEEE Engineering Education and Training. https://ieeexplore.ieee.org/abstract/document/8289838
Marcelino, S. M., Lima, T. M., & Gaspar, P. D. (2023). Lean laboratory—Designing an application of Lean for teaching and research laboratories. Designs, 7(1), 17. https://doi.org/10.3390/designs7010017
Masera, G. (2024). Environmental ergonomics and lab adaptability in climate-affected regions. In Springer Handbook on Sustainable Infrastructure Design. https://link.springer.com/content/pdf/10.1007/978-3-319-00269-9.pdf
Mueller, F., & Schmidt, L. (2022). Optimizing ventilation in chemical laboratories using CFD. Environmental Science and Technology, 25(6), 112–125.
Murray, N., Buckley, J., & Rowan, N. J. (2023). Processing of reusable medical devices: A safety redesign using immersive education. Science of the Total Environment, 897, 165382.
National Fire Protection Association. (2021). NFPA 45: Standard on fire protection for laboratories using chemicals. Retrieved July 5, 2025, from https://www.nfpa.-org/codes-and-standards
National Open University of Nigeria. (2025). SED 835 Laboratory Design and Management. Retrieved July 5, 2025, from https://nou.edu.ng/coursewarecontent/SED%20835%20LABORATORY%20DESIGN%20AND%20MANAGEMENT.pdf
National Renewable Energy Laboratory (NREL). (2018). High-Performance Laboratory Design.
Nelson, J., Carter, P., & Brown, L. (2021). Visual cues in laboratory design: Impact on workflow and safety. Journal of Environmental Design, 17(3), 89–97.
Occupational Safety and Health Administration. (2020). Laboratory safety guidance (OSHA 3404-11R). Retrieved July 5, 2025, from https://www.osha.gov/sites/default/files/publications/OSHA3404laboratory-safety-guidance.pdf
Ochekwu, E. B., Albert, C. O., & Isife, B. I. (2023). Environmental challenges awareness in Nigeria. African Journal of Environment and Natural Science Research, 5(2), 1–14. https://doi.org/10.52589/AJENSR
Okafor, U. P., & Eze, C. C. (2022). Cost-effective laboratory design solutions for Nigerian universities. African Journal of Science and Technology, 14(3), 78–85.
Okeke, C. E., Adeyemi, O., & Ibrahim, A. (2024). Low-cost ventilation solutions for African laboratories. Journal of Sustainable Technology, 10(2), 34–42.
Osibanjo, O., & Wahab, B. (2023). Sustainable laboratory design in developing countries. African Journal of Science and Technology, 14(1), 56–63.
Pimenta, A., Santos, R., & Ferreira, M. (2021). Lean laboratories: Enhancing efficiency through layout design. Journal of Laboratory Management, 13(2), 34–41.
Raj, P., & Raman, A. (2018). Software-defined cloud centers: Lean and green optimization in smart labs. Springer. https://link.springer.com/content/pdf/10.1007/978-3-319-78637-7.pdf
Sartor, D., Heck, S., & Smith, R. (2000). Energy-efficient laboratory design: Strategies for sustainability. ASHRAE Journal, 42(9), 54–62.
Schummer, J., & Spector, T. I. (2007). The visual image of chemistry. Hyle: International Journal for Philosophy of Chemistry, 13(1), 3–41.
Smith, J., & Jones, R. (2019). Ergonomic interventions in laboratory settings: Impact on worker comfort and productivity. Journal of Occupational Health, 10(4), 67–80.
Smith, P., Brown, T., & Garcia, M. (2021). Redesigning biomedical laboratories for safety and efficiency. Biosafety Journal, 8(1), 23–35.
Srinath, A. (2010). Laboratory design concepts for effective utilization of resources and obtaining greater efficacy. International Journal of Emerging Technologies in Learning (iJET), 5(3), 25–30. https://doi.org/10.3991/ijet.v5i3.1323.
Szigeti, F., Davis, G., & Hammond, D. (2005). The impact of laboratory design on research productivity: A quantitative analysis. Facilities Management Journal, 23(7/8), 312–325
Tang, C. J., & Austin, S. A. (2020). A framework for optimizing laboratory design through spatial-functional analysis. Journal of Building Engineering, 32, 101590.
Tseng, M. M., Wang, Y., & Jiao, R. J. (2018). Modular Design. In: CIRP Encyclopedia of Production Engineering. Springer.
Ukoba, K., & Jen, T. C. (2025). Process optimization and lean implementation in African biomedical labs. In Shaping Tomorrow: Thin Films and 3D Printing in the Global South (pp. 56–78). Springer. https://link.springer.com/chapter/10.1007/978-3-031-84124-8_4
University of Washington Environmental Health & Safety Department. (2014). Laboratory safety design guide. Retrieved July 5, 2025, from https://www.ehs.washington.edu/-system/files/resources/LabSafetyDesignGuide.pdf
Walensky, R. P., Ciaranello, A. L., Park, J.-E., & Freedberg, K. A. (2010). Cost-Effectiveness of Laboratory Monitoring in Sub-Saharan Africa: A Review of the Current Literature. Clinical Infectious Diseases, 51(1), 85–92. http://www.jstor.org/stable/25679966.
Watch, D. (2001). Building type basics for research laboratories. New York, NY: John Wiley & Sons, Inc.
World Health Organization. (2020). Laboratory biosafety manual (4th ed.). Geneva: WHO Press. Retrieved July 5, 2025, from https://www.who.int/publications
Yoon, Y. S., Kim, S. J., & Lee, J. H. (2016). Evaluation of laboratory layout effectiveness based on flow patterns and safety zones. Applied Ergonomics, 55, 193–201.
Yousif, I., El Kalach, F., Burns, L., & Harik, R. (2025). Leveraging computer vision and CFD to optimize smart industrial laboratories. Journal of Intelligent Manufacturing, 36, 145–163. https://link.-springer.com/article/10.1007/s10845-024-02396-1
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